Title of article
Highly efficient Cu(I)-catalyzed trifluoromethylation of aryl(heteroaryl) enol acetates with CF3 radicals derived from CF3SO2Na and TBHP at room temperature
Author/Authors
Lu، نويسنده , , Yang and Li، نويسنده , , Yaming and Zhang، نويسنده , , Zhuo-Rong and Jin، نويسنده , , Kun and Duan، نويسنده , , Chunying، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2014
Pages
6
From page
128
To page
133
Abstract
An efficient method for the Cu(I)-catalyzed synthesis of α-trifluoromethyl ketones via the addition of CF3 to aryl(heteroaryl) enol acetates by using the readily available CF3SO2Na (Langlois reagent) has been developed. The reaction is experimentally simple and carried out at room temperature, providing good to excellent yields with wide functional group tolerance.
Keywords
trifluoromethylation , Enol acetates , Synthetic methods , radical addition , ?-CF3 ketone
Journal title
Journal of Fluorine Chemistry
Serial Year
2014
Journal title
Journal of Fluorine Chemistry
Record number
1612244
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