Author/Authors :
Kéki، نويسنده , , Sلndor and Batta، نويسنده , , Gyula and Bereczki، نويسنده , , Ilona and Fejes، نويسنده , , Zsolt L. Nagy، نويسنده , , Lajos and Zajلcz، نويسنده , , ءgnes and Kandra، نويسنده , , Lili and Kiricsi، نويسنده , , Imre and Deلk، نويسنده , , Gyِrgy and Zsuga، نويسنده , , Miklَs and Herczegh، نويسنده , , Pلl، نويسنده ,
Abstract :
We describe the synthesis of new types of α-amylase enzyme-inhibitory polysaccharides obtained by polycondensation of 3,6-Di-O-acetyl-d-glucal followed by deacetylation. The structure of the resulting new polysaccharides containing unique 2,3-unsaturated hexopyranose repeating units were unambiguously determined by NMR and MALDI-TOF MS methods. The deacetylated polysaccharides proved to be a semicompetitive inhibitor of the human salivary amylase enzyme.
Keywords :
Ferrier rearrangement , Unsaturated glycals , Polycondensation , MALDI-TOF MS , NMR
