Title of article :
Structural analysis of dextrins and characterization of dextrin-based biomedical hydrogels
Author/Authors :
Silva، نويسنده , , Dina M. and Nunes، نويسنده , , Clلudia and Pereira، نويسنده , , Isabel C. Moreira، نويسنده , , Ana S.P. and Domingues، نويسنده , , Maria Rosلrio M. and Coimbra، نويسنده , , Manuel A. and Gama، نويسنده , , Francisco M.، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2014
Abstract :
The characterization of several commercial dextrins and the analysis of the potential of dextrin derived hydrogels for biomedical applications were performed in this work. The structural characterization of dextrins allowed the determination of the polymerization and branching degrees, which ranged from 6 to 17 glucose residues and 2 to 13%, respectively. Tackidex, a medical grade dextrin was choosen for further characterization.
mbination of hydrogel with a dextrin nanogel and urinary bladder matrix was achieved without compromising the mechanical properties or microstructure. The encapsulation of cells, preserving its viability, confirms the biocompatibility of the injectable hydrogels, which have therefore great potential for biomedical applications.
Keywords :
Injectable hydrogels , MALDI-MS , Structural analysis , Dextrin , SEC
Journal title :
CARBOHYDRATE POLYMERS
Journal title :
CARBOHYDRATE POLYMERS