Diastereoselective synthesis of 2-aryl-3-aminoazepanes via a novel ring-enlargement process
Author/Authors :
Cutri، نويسنده , , Sabrina and Bonin، نويسنده , , Martine and Micouin، نويسنده , , Laurent and Froelich، نويسنده , , Olivier and Quirion، نويسنده , , Jean-Charles and Husson، نويسنده , , Henri-Philippe Husson، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Pages :
4
From page :
1179
To page :
1182
Abstract :
Syntheses of optically pure 2-aryl-3-aminoazepanes derived from 2-cyano 6-oxazolopiperidine are described. The key step involves a one-pot reduction and ring-enlargement process occurring in a highly regio- and stereoselective way.
