A continuous Michael and aldol coupling of α,β-enones catalyzed by iridium complexes

Ir[(COD)(PPh3)2]OTf activated by H2 molecule catalyzes Michael-type coupling of α,β-enones with enoxysilanes to give 1,5-dicarbonyl compounds after the subsequent protodesilylation. An identical catalyst system makes it possible to attain a continuous Michael and aldol modification toward α,β-enones in a one-pot operation.