Title of article
Solid phase synthesis of oligoureas using O-succinimidyl-(9H-fluoren-9-ylmethoxycarbonylamino)ethylcarbamate derivatives as activated monomers
Author/Authors
Guichard، نويسنده , , Gilles and Semetey، نويسنده , , Vincent and Rodriguez، نويسنده , , Marc and Briand، نويسنده , , Jean-Paul، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
5
From page
1553
To page
1557
Abstract
An efficient stepwise synthesis of oligoureas (up to the nonamer) on solid support using O-succinimidyl-(9H-fluoren-9-ylmethoxycarbonylamino)ethylcarbamate derivatives as activated monomers is described. These building blocks were readily prepared starting from N-Fmoc-protected β3-amino acids via Curtius rearrangement of the corresponding acyl azides and treatment of the resulting isocyanate with N-hydroxysuccinimide.
Keywords
Oligomers , Ureas , solid-phase synthesis , Carbamates
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1636527
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