Author/Authors :
Bernsmann، نويسنده , , Heiko and Hungerhoff، نويسنده , , Benno and Fechner، نويسنده , , Regina and Frِhlich، نويسنده , , Roland and Metz، نويسنده , , Peter، نويسنده ,
Abstract :
Using sultone chemistry, a short and highly enantioselective synthesis of an advanced precursor for the larger hydroxy acid moiety and of the complete smaller hydroxy acid portion of the macrodiolide antibiotic pamamycin-607 has been accomplished.
Keywords :
antibiotics , Diels–Alder reactions , sultones , Desulfurization