Title of article :
Efficient and regioselective 4-amino-de-chlorination of 2,4,6-trichloropyrimidine with N-sodium carbamates
Author/Authors :
Zanda، نويسنده , , Matteo and Talaga، نويسنده , , Patrice and Wagner، نويسنده , , Alain and Mioskowski *، نويسنده , , Charles، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
4-N-Alkoxycarbonyl-2,6-dichloropyrimidines have been synthesized with good to excellent regioselectivity and yields from 2,4,6-trichloropyrimidine and N-sodium carbamates in DMF, at room temperature, in 15–30 minutes.
Keywords :
regioselection , Carbamates , pyrimidines , amination
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
