Title of article :
A new, efficient entry to nucleoside 2′,3′-O,O-cyclophosphorothioates
Author/Authors :
Jankowska، نويسنده , , Jadwiga and Wenska، نويسنده , , Ma?gorzata and Popenda، نويسنده , , Mariusz and Stawi?ski، نويسنده , , Jacek and Kraszewski، نويسنده , , Adam، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
The reaction of 5′-protected ribonucleosides with diphenyl H-phosphonate in pyridine furnished rapid formation of the corresponding 2′,3′-cyclic H-phosphonates 3, which upon sulfurisation and the subsequent removal of the 5′-protecting group, afforded nucleoside 2′,3′-O,O-cyclophosphorothioates 5 in high yields.
Keywords :
Nucleotides , Synthesis , cyclic phosphorothioates , nucleosides
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
