• Title of article

    Platinum catalysed hydrolytic amidation of unactivated nitriles

  • Author/Authors

    Cobley، نويسنده , , Christopher J and van den Heuvel، نويسنده , , Marco and Abbadi، نويسنده , , Abdelilah and de Vries *، نويسنده , , Johannes G، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2000
  • Pages
    4
  • From page
    2467
  • To page
    2470
  • Abstract
    The platinum(II) complex, [(Me2PO··H··OPMe2)PtH(PMe2OH)], efficiently catalyses the direct conversion of unactivated nitriles to N-substituted amides with both primary and secondary amines. Possible mechanisms for this reaction are discussed and evidence for initial amidine formation is reported. Isolated yields vary from 51–89%.
  • Keywords
    Homogeneous catalysis , Nitriles , Amides , Platinum compounds
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2000
  • Journal title
    Tetrahedron Letters
  • Record number

    1636817