Title of article :
Platinum catalysed hydrolytic amidation of unactivated nitriles
Author/Authors :
Cobley، نويسنده , , Christopher J and van den Heuvel، نويسنده , , Marco and Abbadi، نويسنده , , Abdelilah and de Vries *، نويسنده , , Johannes G، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
The platinum(II) complex, [(Me2PO··H··OPMe2)PtH(PMe2OH)], efficiently catalyses the direct conversion of unactivated nitriles to N-substituted amides with both primary and secondary amines. Possible mechanisms for this reaction are discussed and evidence for initial amidine formation is reported. Isolated yields vary from 51–89%.
Keywords :
Homogeneous catalysis , Nitriles , Amides , Platinum compounds
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
