Title of article :
The brucine N-oxide-promoted asymmetric Pauson–Khand reaction
Author/Authors :
Kerr، نويسنده , , William J and Lindsay، نويسنده , , David W. and Rankin، نويسنده , , Elaine M and Scott، نويسنده , , James S and Watson، نويسنده , , Stephen P، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
The brucine N-oxide-mediated asymmetric Pauson–Khand reaction has been further investigated. It was found that the best levels of enantioselection were obtained with substituted propargylic alcohol complexes. The studies also revealed that when acetone or 1,2-dimethoxyethane is used as the reaction solvent, enhanced levels of enantioselectivity, up to an enantiomeric ratio of 11:89, are achieved.
Keywords :
cyclopentenones , amine N-oxides , asymmetric synthesis , cobalt and compounds , Pauson–Khand reactions
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
