Author/Authors :
Takemoto، نويسنده , , Yoshiji and Baba، نويسنده , , Yasutaka and Saha، نويسنده , , Goutum and Nakao، نويسنده , , Syusuke and Iwata، نويسنده , , Chuzo and Tanaka *، نويسنده , , Tetsuaki and Ibuka، نويسنده , , Toshiro، نويسنده ,
Abstract :
The total synthesis of halicholactone by using the chirality of (diene)Fe(CO)3 complexes was reported. The key steps of the synthesis include catalytic asymmetric alkylation, regio- and stereoselective phenylsulfenylation, regio- and stereoselective cyclopropanation and formation of a nine-membered lactone by ring-closing metathesis.
Keywords :
iron and compounds , Cyclopropanation , ring-closing metathesis , total synthesis , halicholactone
