Title of article
A facile synthesis of 7-amino-3-desacetoxycephalosporanic acid derivatives by indium-mediated reduction of 3-iodomethylcephems in aqueous media
Author/Authors
Chae، نويسنده , , Hyungsun and Cho، نويسنده , , Sangwon and Keum، نويسنده , , Gyochang and Kang، نويسنده , , Soon Bang and Pae، نويسنده , , Ae Nim and Kim، نويسنده , , Youseung، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
3
From page
3899
To page
3901
Abstract
An efficient reductive conversion of 3-iodomethylcephalosporin and 3-acetoxymethylcephalosporin derivatives mediated by indium into the corresponding 3-methylcephems and 3-methylenecephams in moderate to good yields has been developed in an aqueous system. 3-Methylenecephams are converted into the corresponding 3-methylcephems under previously reported basic conditions quantitatively.
Keywords
halogens and compounds , indium and compounds , Dehalogenation , water , reactions in , Cephalosporin
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1637663
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