• Title of article

    Stereochemistry and total synthesis of janolusimide, a tripeptide marine toxin

  • Author/Authors

    Giordano، نويسنده , , Assunta and Della Monica، نويسنده , , Carmela and Landi، نويسنده , , Francesco and Spinella *، نويسنده , , Aldo and Sodano *، نويسنده , , Guido، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2000
  • Pages
    4
  • From page
    3979
  • To page
    3982
  • Abstract
    The stereochemistry of janolusimide, a lipophilic tripeptide marine toxin, has been fully elucidated by stereoselective synthesis of the lactam component (5S)-3,3′-dimethyl-5-isopropylpyrrolidin-2,4-dione. The peptide was then synthesized in 13 steps and in 0.8% total yield.
  • Keywords
    Marine metabolites , molluscs , Imides , Peptides
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2000
  • Journal title
    Tetrahedron Letters
  • Record number

    1637696