Author/Authors :
Fukuda ، نويسنده , , Yoshio and Sakurai، نويسنده , , Masahiro and Okamoto، نويسنده , , Yasushi، نويسنده ,
Abstract :
An effective method for the synthesis of (±)-AM6898D and its three diastereoisomers has been established via Claisen rearrangement, stereoselective epimerization of the α-ester stereochemistry and introduction of one isoprene unit by umpolung.