A new polymer-bound N-hydroxysuccinimidyl active ester linker
Author/Authors :
Shao، نويسنده , , Hui and Zhang، نويسنده , , Qiang and Goodnow، نويسنده , , Robert and Chen، نويسنده , , Li and Tam، نويسنده , , Steve، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Pages :
4
From page :
4257
To page :
4260
Abstract :
Synthesis of a new N-hydroxysuccinimidyl resin is described and the N-acylation with this resin provides amide products in high yields and excellent purities. This new linker is suitable for combinatorial library synthesis.
Keywords :
and combinatorial chemistry , solid-phase synthesis , acylation , Amides