Title of article :
A sultone approach to the C(1)–C(18) moiety of pamamycin-607
Author/Authors :
Bernsmann، نويسنده , , Heiko and Frِhlich، نويسنده , , Roland and Metz، نويسنده , , Peter، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
A highly advanced enantiomerically pure C(1)–C(18) precursor of the larger fragment of the macrodiolide pamamycin-607 has been synthesized. The stereotriad C(7)–C(9) between the two heterocyclic rings of the target was generated using a diastereoselective hydroboration controlled by minimization of allylic 1,3-strain.
Keywords :
Diels–Alder reactions , sultones , Hydroboration , antibiotics
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
