Title of article :
Enantioselective synthesis of 1,1,1-trifluoroalkan-2-ols by ruthenium-catalyzed hydrogenation
Author/Authors :
Kuroki، نويسنده , , Yoshichika and Asada، نويسنده , , Daisuke and Sakamaki، نويسنده , , Yuko and Iseki، نويسنده , , Katsuhiko، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
The highly enantioselective synthesis of 1,1,1-trifluoroalkan-2-ols has been achieved by hydrogenating 1,1,1-trifluoroalkan-2-one enol acetates in the presence of chiral ruthenium catalysts. An enol acetate, 2-acetoxy-3,3,3-trifluoro-1-(phenylthio)propene, can be successfully transformed into enantiomerically pure trifluorolactic acid.
Keywords :
Catalysts , Fluorine and compounds , asymmetric synthesis , Hydrogenation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
