Title of article :
Total synthesis of a marine imidazole alkaloid, clathridine A
Author/Authors :
Ohta، نويسنده , , Shunsaku and Tsuno، نويسنده , , Naoki and Maeda، نويسنده , , Kazushi and Nakamura، نويسنده , , Seikou and Taguchi، نويسنده , , Norio and Yamashita، نويسنده , , Masayuki and Kawasaki، نويسنده , , Ikuo، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
The first total synthesis of clathridine A (8), a marine imidazole alkaloid, was achieved by using a novel regioselective condensation as a key step, in which preclathridine A (2) was treated with 1-methylparabanic acid (11) in the presence of a silylating agent.
Keywords :
clathridine A , preclathridine A , marine alkaloid , parabanic acid , regioselective condensation , Imidazole , total synthesis
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
