Title of article
Design and synthesis of macro-heterocycles structurally related to tirofiban
Author/Authors
Ramaseshan، نويسنده , , Mahesh and Robitaille، نويسنده , , Martin and Ellingboe، نويسنده , , John W and Dory، نويسنده , , Yves L and Deslongchamps *، نويسنده , , Pierre، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
6
From page
4737
To page
4742
Abstract
Sequences of nine and four steps were designed to yield two tirobifan related macrocycles by SN2 macrocyclization. The cyclic compounds contain the amino acid tyrosine, one insaturation and are either 18- or 20-membered rings. All the reaction conditions are very mild and the overall yields indicate that the results depend a lot on the structure of the targets and on the length of the reaction sequence.
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1638025
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