Title of article
Synthesis and asymmetric hydrogenation of 3,5-dioxoheptanedioates. Preparation of enantiomerically pure substituted δ-valerolactones
Author/Authors
Katarzyna Kiegiel، نويسنده , , Jaros?aw and J??wik، نويسنده , , Julita and Wo?niak، نويسنده , , Krzysztof and Jurczak، نويسنده , , Janusz، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
5
From page
4959
To page
4963
Abstract
The synthesis of 3,5-dioxoheptanedioic acid derivatives based on the reaction of ketene with malonyl chloride was developed. Resulting diketones were subjected to Ru–(S)-BINAP-catalyzed asymmetric hydrogenation. The products were transformed into enantiomerically pure 3,5-substituted-δ-valerolactones.
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1638112
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