Title of article
Easy and efficient synthesis of enantiomerically enriched 2H-azirines derived from phosphonates
Author/Authors
Palacios، نويسنده , , Francisco and Ochoa de Retana، نويسنده , , Ana C. and Gil، نويسنده , , José I، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
5363
To page
5366
Abstract
An efficient synthesis of 2H-azirines substituted with a phosphonate group is described. The key step is an alkaloid-mediated Neber reaction of β-ketoxime tosylates. Reduction of 2H-azirines with sodium borohydride in ethanol gives 2-phosphorylated cis-aziridines.
Keywords
azirines , Aziridines , asymmetric synthesis , oximes , Phosphonates , Aminophosphonates
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1638209
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