Title of article
An efficient two-step synthesis of mono-, di- and triureas from resin-bound amides
Author/Authors
Nefzi، نويسنده , , Adel and Ong، نويسنده , , Nhi A and Houghten، نويسنده , , Richard A، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
6
From page
5441
To page
5446
Abstract
An efficient method for the solid-phase synthesis of mono-, di- and triureas from resin-bound monoamines, diamines and triamines is described. The exhaustive reduction of solid support-bound amides generated the requisite amines, which, following treatment with isocyanates and cleavage, provided the corresponding ureas in high purity and good yields.
Keywords
Combinatorial chemistry , triurea , solid-phase synthesis , urea , diurea , Peptidomimetics
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1638226
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