Title of article
Enantiospecific synthesis of (−)-3-iso-19,20-dehydro-β-yohimbine from secologanin: a route to normal and pseudo stereoisomers of yohimbine
Author/Authors
Brown، نويسنده , , Richard T and Pratt، نويسنده , , Simon B and Richards، نويسنده , , Paul، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
5627
To page
5630
Abstract
Hydrolysis of secologanin ethylene acetal at pH 7 resulted in stereoselective aldol cyclisation to a cyclohexene aldehyde, which, on reductive amination and cyclisation with tryptamine afforded (−)-3-iso-19,20-dehydro-β-yohimbine, converted into various normal and pseudo isomers of yohimbine.
Keywords
aldol , Alkaloids , biomimetic , indole , terpene , stereoselection
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1638264
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