• Title of article

    Indium(I) bromide-mediated bromocyanomethylation of carbonyl compounds

  • Author/Authors

    Nَbrega، نويسنده , , J.A. and Gonçalves، نويسنده , , Simone M.C. and Peppe، نويسنده , , C.، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2000
  • Pages
    4
  • From page
    5779
  • To page
    5782
  • Abstract
    Bromocyanomethylation of a variety of carbonyl compounds to produce the corresponding 2-bromo-3-hydroxynitriles has been achieved in moderate to good yields by the action of dibromoacetonitrile and indium(I) bromide. Moderate diastereoselectivity was observed. Exclusive mono-coupling at the carbonyl group was found with 1,2-diketones and α-haloketones.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2000
  • Journal title
    Tetrahedron Letters
  • Record number

    1638295