Title of article
New method for activation of aldimines in cycloaddition of lithium ynolates with N-2-methoxyphenyl imines leading to β-lactams
Author/Authors
Shindo، نويسنده , , Mitsuru and Oya، نويسنده , , Soichiro and Murakami، نويسنده , , Ryoko and Sato، نويسنده , , Yusuke and Shishido، نويسنده , , Kozo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
5943
To page
5946
Abstract
The cycloaddition of the N-2-methoxyphenyl aldimines with lithium ynolates was efficiently accelerated via chelation to give β-lactam enolates, which immediately reacted with one more equivalent of the imine to give β-lactams (2:1 adducts) in good yields, while N-4-methoxyphenyl imines were inert towards lithium ynolates.
Keywords
Ynolates , imines , azetidinones , chelation
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1638330
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