Title of article :
Highly E-selective synthesis of α,β-unsaturated amides from N-2-methoxyphenyl aldimines via lithium ynolates
Author/Authors :
Shindo، نويسنده , , Mitsuru and Oya، نويسنده , , Soichiro and Murakami، نويسنده , , Ryoko and Sato، نويسنده , , Yusuke and Shishido، نويسنده , , Kozo، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
Lithium ynolates reacted with N-2-methoxyphenyl (OMP) aldimines to afford α,β-unsaturated amides in excellent E-selectivity via a retro-Mannich reaction of the 2:1 adducts (β-lactams), followed by cleavage of the β-lactam enolates.
Keywords :
Ynolates , Olefination , Amides , imines
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
