Author/Authors :
Overkleeft، نويسنده , , Herman S and Bos، نويسنده , , Pepijn R and Hekking، نويسنده , , Brian Francis and Gordon Harris، نويسنده , , Eva J and Ploegh، نويسنده , , Hidde L and Kessler، نويسنده , , Benedikt M، نويسنده ,
Abstract :
The solid phase synthesis of the known proteasome inhibitor ZL3VS, using Kennerʹs safety catch protocol, is described. This methodology has been extended to the synthesis of various novel peptide vinyl sulfone and peptide epoxyketone derivatives.