A concise synthesis of the HIV-protease inhibitor nelfinavir via an unusual tetrahydrofuran rearrangement
Author/Authors :
Zook، نويسنده , , Scott E and Busse، نويسنده , , Juliette K and Borer، نويسنده , , Bennett C، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Pages :
5
From page :
7017
To page :
7021
Abstract :
An efficient synthesis of nelfinavir 1 was developed. The synthesis features an unusual rearrangement of a 3-amidotetrahydrofuran into a functionalized oxazoline.
