Title of article :
A novel highly stereoselective total synthesis of epothilone B and of its (12R,13R) acetonide
Author/Authors :
Mulzer، نويسنده , , Johann and Karig، نويسنده , , Gunter and Pojarliev، نويسنده , , Peter، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
Stereoselective syntheses of epothilone B (1) and its novel derivative 2 are described. Key steps are the formation of intermediate 3 via Sharpless AD-reaction and Davis–Evans-hydroxylation.
Keywords :
asymmetric synthesis , Antitumor compounds , Oxazolidinone , hydroxylation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
