• Title of article

    Dihydroxyverbacine is the terminal precursor in the biosynthesis of aphelandrine and orantine

  • Author/Authors

    Nezbedovل، نويسنده , , Lenka and Hesse، نويسنده , , Manfred and Drandarov، نويسنده , , Konstantin and Werner، نويسنده , , Christa، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2000
  • Pages
    4
  • From page
    7859
  • To page
    7862
  • Abstract
    A microsomal-bond cytochrome P-450 enzyme system has been discovered in the roots of Aphelandra squarrosa that is responsible for the stereospecific intramolecular phenol coupling of (S)-dihydroxyverbacine to aphelandrine. The biogenesis of the closely related alkaloids orantine (ephedradine A) and ephedradines B, C and D should follow a similar biogenetic pattern.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2000
  • Journal title
    Tetrahedron Letters
  • Record number

    1639208