Stereoselective hydrogen bromide-promoted hydrogenation of an α-hydroxyoxime
Author/Authors :
Davies، نويسنده , , Ian C. and Taylor، نويسنده , , Mark and Marcoux، نويسنده , , Jean-François and Matty، نويسنده , , Louis and Wu، نويسنده , , Jimmy and Hughes، نويسنده , , David and Reider، نويسنده , , Paul J، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Pages :
5
From page :
8021
To page :
8025
Abstract :
Hydrogen bromide has been demonstrated to provide optimal cis-selectivity in the reduction of 4-chromanone α-hydroxyoxime (25:1 cis/trans) in 94% yield. This reaction is pivotal in the synthesis of cis-aminochromanol.
