Title of article
Micellar electrokinetic capillary chromatography as an alternative method for the determination of ethinylestradiol and levo-norgestrel
Author/Authors
Berzas، نويسنده , , J.J and Del Castillo، نويسنده , , B and Castaٌeda، نويسنده , , G and Pinilla، نويسنده , , M.J، نويسنده ,
Issue Information
ماهنامه با شماره پیاپی سال 1999
Pages
8
From page
261
To page
268
Abstract
A method for quantifying of ethinylestradiol (ETE) and levo-norgestrel (LEV) in pharmaceutical products by micellar electrokinetic chromatography (MEKC) is described. The separation was carried out at 25°C and 25 kV, using a 20 mM borate buffer (pH 9.2), 15 mM sodium dodecylsulfate (SDS) in 30% acetonitrile/water (v/v). Under these conditions the analysis takes about 7 min. The method has been applied for quantifying both compounds in six different commercial contraceptives and the proposed method gave good results when compared with a reference liquid chromatographic (LC) method.
Keywords
Ethinylestradiol , Micellar electrokinetic chromatography (MEKC) , Levo-norgestrel , ORAL CONTRACEPTIVES
Journal title
Talanta
Serial Year
1999
Journal title
Talanta
Record number
1639366
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