Title of article :
4,6-Dichloro-5-nitropyrimidine: a versatile building block for the solid phase synthesis of dihydropteridinones
Author/Authors :
Baxter، نويسنده , , Anthony D and Boyd، نويسنده , , E.Andrew and Cox، نويسنده , , Philip B and Loh Jr.، نويسنده , , Vincent and Monteils، نويسنده , , Claude and Proud، نويسنده , , Andrew، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
This letter describes a novel, flexible, solid phase route to pyrimidine-based heterocycles that utilises commercially available 4,6-dichloro-5-nitropyrimidine. This was exemplified by the synthesis of dihydropteridinones.
Keywords :
Combinatorial chemistry , 6-dichloro-5-nitropyrimidine , Solid phase synthesis , dihydropteridinones , 4
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
