Author/Authors :
Matsumoto، نويسنده , , Takashi and Yamaguchi، نويسنده , , Hiroki and Hamura، نويسنده , , Toshiyuki and Tanabe، نويسنده , , Mitsujiro and Kuriyama، نويسنده , , Yokusu and Suzuki، نويسنده , , Keisuke، نويسنده ,
Abstract :
An efficient synthetic route to 3-(phenylsulfonyl)phthalides possessing a β-C-olivoside was developed by exploiting the regioselective [2+2] cycloaddition of benzyne with ketene silyl acetal. The compounds are useful in the total synthesis of the angucyclines, including aquayamycin.
