Author/Authors :
Organ، نويسنده , , Michael G and Kaldor، نويسنده , , Stephen W and Dixon، نويسنده , , Craig E and Parks، نويسنده , , Daniel J and Singh، نويسنده , , Upinder and Lavorato، نويسنده , , David J and Isbester، نويسنده , , Paul K and Siegel*، نويسنده , , Miles G، نويسنده ,
Abstract :
A solution-phase, multi-reaction sequence has been developed for the parallel synthesis of ethanolamine libraries. This approach uses 2,3-dibromopropene as a template for the synthesis of a small olefin sub-library, which is then further functionalized to form the final ethanolamine library. The methodology is demonstrated by the synthesis of a 5×4 array of ethanolamines.