Author/Authors :
Abdel-Aziz، نويسنده , , Alaa A.-M and Okuno، نويسنده , , Junko and Tanaka، نويسنده , , Shinsuke and Ishizuka، نويسنده , , Tadao and Matsunaga، نويسنده , , Hirofumi and Kunieda، نويسنده , , Takehisa، نويسنده ,
Abstract :
Diastereoselectivity which is induced by the use of 2-imidazolidinone auxiliaries is greatly dependent on the N-substituents of the heterocycles, among which the bulky arenesulfonyl group is the moiety of choice. Reactions of this type afford an excellent level of diastereoselection in the methylation of N′-butyryl-2-imidazolidinones via the metal enolates.
