Title of article
Conjugation of amino acid O-methyl esters with AZT-5′-O-phosphorothioate and phosphorodithioate
Author/Authors
Baraniak، نويسنده , , Janina and Kaczmarek، نويسنده , , Renata and Stec، نويسنده , , Wojciech J.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
9139
To page
9142
Abstract
Based upon 1,3,2-oxathia(-dithia)phospholane chemistry, 5′-O-derivatisation of AZT with the O-methyl esters of l-phenylalanine and l-tryptophan was performed and the corresponding 5′-aminoacidophosphoramidothioates or phosphoramidodithioates of AZT were obtained in satisfactory yield.
Keywords
AZT , N-phosphorothioylated amino acid , oxathia(-dithia)phospholane ring-opening condensation
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1640055
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