Author/Authors :
Costantino، نويسنده , , Valeria and Imperatore، نويسنده , , Concetta and Fattorusso، نويسنده , , Ernesto and Mangoni، نويسنده , , Alfonso، نويسنده ,
Abstract :
Glycals can be converted into the corresponding 2-deoxysugars in good yields by treatment with N-iodosuccinimide in CH3CN–H2O 95:5 and removal of the iodide group using Na2S2O4 in DMF/H2O at room temperature. This method is easy to apply, sufficiently mild to allow the survival of acid-sensitive groups such as silyl and trityl ethers and less harmful to the environment than metal-based reactions.