• Title of article

    ‘One-pot’ nitro reduction–cyclisation solid phase route to benzimidazoles

  • Author/Authors

    Wu، نويسنده , , Zemin and Rea، نويسنده , , Philip and Wickham، نويسنده , , Geoffrey، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2000
  • Pages
    4
  • From page
    9871
  • To page
    9874
  • Abstract
    An improved solid phase synthesis of benzimidazoles is described. A polymer-bound o-nitroaniline was reacted with aldehydes in DMF in the presence of SnCl2·2H2O at 60°C for three hours to give benzimidazoles in excellent purity and good yield after TFA cleavage. A library of 25 benzimidazoles was prepared using this ‘one-pot’ procedure.
  • Keywords
    Solid phase synthesis , Benzimidazole , SynPhase™ Lantern
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2000
  • Journal title
    Tetrahedron Letters
  • Record number

    1640543

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1640543