The synthesis of highly functionalized seven-membered allyl ethers using palladium-catalyzed alkoxyallylation of activated olefins and ring-closing olefin metathesis

The investigation of palladium-catalyzed alkoxyallylation of activated olefins, followed by ring-closing metathesis to synthesize functionalized seven-membered ring allyl ethers is described. The influence of the olefin substituents on the diastereoselectivity of the alkoxyallylation has also been examined.