• Title of article

    Novel aromatic substances, dictyomedin A and B, from Dictyostelium cellular slime molds and their inhibitory effects on Dictyostelium development

  • Author/Authors

    Takaya، نويسنده , , Yoshiaki and Kikuchi، نويسنده , , Haruhisa and Terui، نويسنده , , Yuichi and Komiya، نويسنده , , Jun and Maeda، نويسنده , , Yasuo and Ito، نويسنده , , Akira and Oshima، نويسنده , , Yoshiteru، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2001
  • Pages
    3
  • From page
    61
  • To page
    63
  • Abstract
    To elucidate the diversity of secondary metabolites of Dictyostelium cellular slime molds and search for physiologically active substances affecting their development, we investigated the constituents of D. medium. From the methanol extract of its fruit body, we obtained two novel aromatic compounds named dictyomedin A (1) and B (2), and their structures were elucidated by means of physicochemical data. Biological evaluation of the compounds showed that they delayed the differentiation of D. discoideum cells.
  • Keywords
    Dictyostelium medium , cellular slime molds , Dibenzofuran , differentiation inhibitor
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2001
  • Journal title
    Tetrahedron Letters
  • Record number

    1640897