Title of article
Synthesis of peptide di-aldehyde precursor for stepwise chemoselective ligations via oxime bonds
Author/Authors
Lelièvre، نويسنده , , Dominique and Buré، نويسنده , , Corinne and Laot، نويسنده , , Fabrice and Delmas، نويسنده , , Agnès، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
4
From page
235
To page
238
Abstract
To synthezise a triple-function branched peptide in a modular way, we present a new strategy based on orthogonal generation of two aldehyde functions from an acetal and a 2-amino alcohol. Successive unmaskings of aldehyde functions of the stem peptide affords stepwise chemoselective ligations of two (aminooxy)acetyl peptides via oxime bonds.
Keywords
peptide aldehyde , branched-peptide , Chemoselective ligation , Oxime
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1641040
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