Title of article
Synthesis of a heterocyclic receptor for carboxylic acids
Author/Authors
Moore، نويسنده , , Gregory and Levacher، نويسنده , , Vincent and Bourguignon، نويسنده , , Jean and Dupas، نويسنده , , Georges، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
261
To page
263
Abstract
The synthesis of a tricyclic receptor having a bowl shape and three binding points for carboxylic acids has been achieved starting from readily available 1-tetralone derivatives. This host possesses a six-membered lactam moiety and a carboxamide at the end of a flexible arm. The association constant with benzoic acid and the stoichiometry of the complex have been determined using 1H NMR dilution experiments.
Keywords
molecular modelling , Molecular recognition , carboxylic acids , coupling reactions
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1641056
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