Author/Authors :
Adam Shih-Yuan Lee، نويسنده , , Adam and Yang، نويسنده , , Hui-Chun and Su، نويسنده , , Feng-Yih، نويسنده ,
Abstract :
A series of carboxylic acids was transformed to their corresponding methyl esters under CBr4/CH3OH (0.05 eq., 5 ml) reaction conditions. The rate of esterification is decreased with increasing bulkiness of the alcohol. Chemoselectivity can be achieved between phenylacetic and benzoic acids, sp3-C and sp2-C acids as well as between sp3-C and sp-C tethered carboxylic acids.
