Title of article
Enantioselective desymmetrization of meso-cyclic anhydrides catalyzed by hexahydro-1H-pyrrolo[1,2-c]imidazolones
Author/Authors
Uozumi، نويسنده , , Yasuhiro and Yasoshima، نويسنده , , Kayo and Miyachi، نويسنده , , Takamasa and Nagai، نويسنده , , Shin-ichi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
4
From page
411
To page
414
Abstract
Asymmetric methanolysis of meso cyclic carboxylic anhydrides including hexahydrophthalic anhydride proceeded in toluene in the presence of (6R,7aS)-(2-aryl-6-hydroxy)hexahydro-1H-pyrrolo[1,2-c]imidazol-1-one to give the corresponding desymmetrized mono ester acids (e.g. (1S,2R)-2-(methoxycarbonyl)cyclohexane-1-carboxylic acid) with enantiomeric excesses of up to 89%.
Keywords
enantioselective desymmetrization , nucleophilic catalyst , 2-c]imidazolone
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1641178
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