Title of article :
Diastereoselective reduction of N-phthaloyl α-amino ketones: synthesis of syn-3-amino-1,2-diol derivatives
Author/Authors :
Sengupta، نويسنده , , Saumitra and Sen Sarma، نويسنده , , Debarati، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
LiAlH(OBu-t)3 reduction of the chiral-pool derived N-phthaloyl α-amino-α′-acetoxy ketones has led to a facile diastereoselective synthesis of syn-3-amino-1,2-diols (>75% de).
Keywords :
?-amino diazoketones , Lithium tri-t-butoxyaluminium hydride , syn-reduction , syn-amino diols
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
