• Title of article

    A catalytic versus stoichiometric photoinduced electron transfer promoted selective C16C21 bond cleavage of catharanthine

  • Author/Authors

    Cocquet، نويسنده , , Guillaume and Rool، نويسنده , , Patrice and Ferroud، نويسنده , , Clotilde، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2001
  • Pages
    3
  • From page
    839
  • To page
    841
  • Abstract
    A clean and efficient access to the cleavamine skeleton is described through the selective oxidative C16C21 bond cleavage of catharanthine. The best result is obtained by the use of catalytic quantities of β-lapachone as photosensitizer, which permits the successful control of competition between the back electron transfer, the deprotonation and the fragmentation pathway.
  • Keywords
    Oxygen , Singlet , photochemistry , Oxidation , Cleavage reactions , Alkaloids
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2001
  • Journal title
    Tetrahedron Letters
  • Record number

    1641517

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1641517