• Title of article

    Synthesis of a model compound of mappicine ketone based on sulfur-directed 5-exo selective aryl radical cyclization onto enamides

  • Author/Authors

    Ishibashi، نويسنده , , Hiroyuki S. Kato، نويسنده , , Issei and Takeda، نويسنده , , Yoshifumi and Tamura، نويسنده , , Osamu، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2001
  • Pages
    3
  • From page
    931
  • To page
    933
  • Abstract
    Enamides 10, upon treatment with Bu3SnH–AIBN, gave 5-exo aryl radical cyclization products 11, which were partially desulfurized to give 1-substituted dihydroisoindoles 7 and 12. This method was applied to the synthesis of a model compound 4 of mappicine ketone (1).
  • Keywords
    Enamides , radicals and radical reactions , antivirals , isoindoles , aryl halides
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2001
  • Journal title
    Tetrahedron Letters
  • Record number

    1641595