Title of article
Diastereoselective synthesis of α-substituted β-amidophosphonates
Author/Authors
Castelot-Deliencourt، Geraldine نويسنده , , Géraldine and Pannecoucke، نويسنده , , Xavier and Quirion، نويسنده , , Jean-Charles، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
4
From page
1025
To page
1028
Abstract
A simple and general asymmetric synthesis of β-amidophosphonates is described. The method involves the highly selective addition (up to 95% d.e.) of diethyl phosphite to various chiral α,β-unsaturated carboxylic amides derived from chiral aminoalcohols.
Keywords
phosphonic acids and derivatives , asymmetric synthesis , Michael addition
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1641679
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